![]() AFM results reveal that the substrates were about 600 nm in height and the surface was very rough. ![]() SEM and TEM images show that the silver substrates were composed of crystallized silver nanoplates with an average thickness of 50 nm. The silver substrate could be shaped into designed patterns, and could be precisely located at the desired position of the microchannel bed, giving the feasibility for real-time detection during reactions. In our work, femtosecond laser direct writing was adopted for highly localizable and controllable fabrication of the SERS monitor through a multi-photon absorption (MPA) induced photoreduction of silver salt solution. ![]() We report here a facile approach for flexible integration of high efficiency surface enhanced Raman scattering (SERS) monitors in a continuous microfluidic channel.
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